The prevention and management of typhoid fever

This article has been cited by other articles in PMC.

The prevention and management of typhoid fever

Typhi is human-restricted, these chronic carriers become the crucial reservoir, which can persist for decades for further spread of the disease, further complicating the identification and treatment of the disease. These areas have a lack of access to clean water, proper sanitation systems, and proper health care facilities.

For these areas, such access to basic public health needs is not in the near future. She was forcibly quarantined as a carrier of typhoid fever in for three years and then again from until her death in In BC, a plaguewhich some believe to have been typhoid fever, killed one-third of the population of Athensincluding their leader Pericles.

Following this disaster, the balance of power shifted from Athens to Spartaending the Golden Age of Pericles that had marked Athenian dominance in the Greek ancient world.

The ancient historian Thucydides also contracted the disease, but he survived to write about the plague. His writings are the primary source on this outbreak, and modern academics and medical scientists consider typhoid fever the most likely cause.

Ina study detected DNA sequences similar to those of the bacterium responsible for typhoid fever in dental pulp extracted from a burial pit dated to the time of the outbreak. A pair of epidemics struck the Mexican highlands in andcausing an estimated 7 to 17 million deaths.

Typhoid fever killed more than settlers in the New World between and This disease may also have been a contributing factor in the death of 12th US President Zachary Taylor due to the unsanitary conditions in Washington, D.

The worst year waswhen the typhoid death rate was perpeople. Major Walter ReedEdward O. Shakespeare, and Victor C. Vaughan were appointed August 18,with Reed being designated the President of the Board. The Typhoid Board determined that during the war, more soldiers died from this disease than from yellow fever or from battle wounds.

A-Z Infectious Diseases -

The Board promoted sanitary measures including latrine policy, disinfection, camp relocation, and water sterilization, but by far the most successful antityphoid method was vaccination, which became compulsory in June for all federal troops.

The most notorious carrier of typhoid fever, but by no means the most destructive, was Mary Mallonalso known as Typhoid Mary. Inshe became the first carrier in the United States to be identified and traced.

She was a cook in New York who was closely associated with 53 cases and three deaths. Mary quit her job, but returned later under a false name. She was detained and quarantined after another typhoid outbreak. She died of pneumonia after 26 years in quarantine.

Development of vaccination[ edit ] During the course of treatment of a typhoid outbreak in a local village inEnglish country doctor William Budd realised the "poisons" involved in infectious diseases multiplied in the intestines of the sick, were present in their excretions, and could be transmitted to the healthy through their consumption of contaminated water.

Almroth Edward Wright developed the first effective typhoid vaccine. InKarl Joseph Eberth described a bacillus that he suspected was the cause of typhoid. Today, the bacillus that causes typhoid fever goes by the scientific name Salmonella enterica entericaserovar Typhi.

Citing the example of the Second Boer Warduring which many soldiers died from easily preventable diseases, Wright convinced the British Army that 10 million vaccine doses should be produced for the troops being sent to the Western Frontthereby saving up to half a million lives during World War I.

For the first time, their casualties due to combat exceeded those from disease. Russella U. It eliminated typhoid as a significant cause of morbidity and mortality in the U. Most developed countries saw declining rates of typhoid fever throughout the first half of the 20th century due to vaccinations and advances in public sanitation and hygiene.

Inthe chlorination of public drinking water was a significant step in the US in the control of typhoid fever. The first permanent disinfection of drinking water in the U.

Credit for the decision to build the chlorination system has been given to John L. Today, the incidence of typhoid fever in developed countries is around five cases per million people per year.Mar 01,  · Typhoid fever, also known as enteric fever, is a potentially fatal multisystemic illness caused primarily by Salmonella enterica, subspecies enterica serovar typhi and, to a lesser extent, related serovars paratyphi A, B, and C.

The protean manifestations of typhoid fever make this disease a true diagnostic challenge. Mary Mallon (September 23, – November 11, ), also known as Typhoid Mary, was an Irish-American cook.

She was the first person in the United States identified as an asymptomatic carrier of the pathogen associated with typhoid was presumed to have infected 51 people, three of whom died, over the course of her career as a cook.

The prevention and management of typhoid fever

She was twice forcibly isolated by public health. WHO/V&B/ ORIGINAL: ENGLISH WHO Background document: The diagnosis,treatment and prevention of typhoid fever World Health Organization . Typhoid Fever Prevention Vaccine. Typhoid fever is an acute febrile illness caused by the bacterium Salmonella typhi.

It is spread by contaminated food and water. The largest burden of typhoid fever falls on the developing world. Because there is no simple diagnostic test for salmonella infections, the importance of typhoid is often underestimated. For any urgent enquiries please contact our customer services team who are ready to help with any problems.

How does typhoid fever affect the body? | Bacterial Infections - Sharecare